Silvia Scaglione | Other | Best Researcher Award

Dr. Silvia Scaglione | Other | Best Researcher Awardot

Chief scientist at React4life, Italy

Silvia Scaglione is a distinguished biomedical engineer and researcher with extensive experience in bioengineering, tissue engineering, and advanced in vitro models. She holds a Ph.D. in Bioengineering and Bioelectronics from the University of Genoa and has served as a researcher at the National Research Council (CNR) of Italy since 2010, currently holding a senior researcher position. She is the founder and Chief Scientist of React4Life, a startup focused on innovative 3D tissue models, and has led multiple high-impact research projects, including European-funded initiatives such as Horizon 2020 and HORIZON-HLTH. Her contributions to biomaterials, regenerative medicine, and organ-on-chip technologies have been recognized through numerous prestigious awards, including the Best Health Innovation award from the European Commission and the Gamma Donna award. Scaglione has been an invited speaker at major international conferences, a scientific evaluator for European research grants, and a reviewer for leading journals. With a strong publication record, patents, and leadership in academia and industry, she has significantly advanced biomedical research, particularly in cancer and regenerative medicine, making her a strong candidate for the Best Researcher Award.

Professional Profile 

Education

Silvia Scaglione holds a Ph.D. in Bioengineering and Bioelectronics from the University of Genoa, where she also earned her Master’s degree in Biomedical Engineering. Her academic journey focused on advanced biomedical technologies, biomaterials, and tissue engineering, laying the foundation for her groundbreaking research in regenerative medicine and organ-on-chip models. Throughout her education, she developed expertise in computational modeling, microfluidics, and cellular biomechanics, which later became central to her work in both academia and industry. Her strong educational background has been instrumental in her role as a senior researcher at the National Research Council (CNR) of Italy and as the founder of React4Life, a startup specializing in innovative 3D tissue models for biomedical applications.

Professional Experience

Silvia Scaglione is a distinguished bioengineer with extensive experience in biomedical research and innovation. She serves as a senior researcher at the National Research Council (CNR) of Italy, where she focuses on tissue engineering, regenerative medicine, and organ-on-chip technologies. She is also the founder and president of React4Life, a biotech company specializing in advanced 3D tissue models for drug testing and personalized medicine. With a strong background in bioengineering, biomaterials, and microfluidics, she has led numerous research projects, published extensively in high-impact journals, and contributed to the development of cutting-edge biomedical technologies. Her expertise bridges academia and industry, driving forward innovative solutions in healthcare and life sciences.

Research Interest

Silvia Scaglione’s research interests lie at the intersection of bioengineering, regenerative medicine, and advanced in vitro modeling. She specializes in developing innovative 3D tissue models, organ-on-chip systems, and microfluidic platforms to improve drug testing, disease modeling, and personalized medicine. Her work focuses on creating physiologically relevant environments that mimic human tissues, enabling more accurate preclinical studies and reducing reliance on animal testing. Additionally, she explores biomaterials, stem cell therapies, and tissue regeneration strategies to advance medical treatments for various diseases. Through her research, she aims to bridge the gap between biomedical engineering and clinical applications, fostering the development of next-generation healthcare solutions.

Award and Honor

Silvia Scaglione has been recognized with several prestigious awards throughout her career, highlighting her contributions to biomedical engineering and innovation. In 2019, she received the ITWIIN Best Inventor Award for her development of MIVO, a patented technology that replicates living organs in the laboratory for testing purposes.In 2021, she was honored with the Women Startup Award powered by Intesa Sanpaolo Innovation Center, acknowledging her role as Chief Research Officer at React4Life and her innovative contributions to the biotech sector.The same year, React4Life, under her leadership, won the Innovation Radar Prize in the Health Tech Innovation category, further cementing her impact on advancing healthcare technologies.Additionally, she was a finalist for the GammaDonna Award in 2021, which celebrates innovative female entrepreneurship in Italy.

Conclusion

Silvia Scaglione is an exceptionally strong candidate for the Best Researcher Award. Her pioneering work in biomedical engineering, leadership in major research projects, industry impact, and multiple prestigious recognitions make her highly deserving of the award. Addressing publication metrics, broader global collaborations, and public science outreach could further solidify her standing in the global research community.

Publications Top Noted

  • Integrating bioprinted oral epithelium with millifluidics for fluorouracil perfusion and Fusobacterium infection to bioengineer oral mucositis-on-a-chip

    • Authors: T.T. Truong, T.V. Phan, Y. Oo, O. Matangkasombut, J.N. Ferreira, et al.
    • Year: 2025
    • Citations: 0
  • Shifting the Focus from Dissolution to Permeation: Introducing the Meso-fluidic Chip for Permeability Assessment (MCPA)

    • Authors: M.M. Tzanova, B.S. Larsen, R. Birolo, M. Hiorth, M.P. di Cagno, et al.
    • Year: 2024
    • Citations: 1
  • Fluid-Dynamic Culture of Tumour and Immune Cells for More Predictive Infiltration Studies and Immunotherapy Drug Screening

    • Authors: M.E.F. Palamà, M. Aiello, S. Scaglione
    • Year: Not specified
    • Citations: 0
  • Multicompartmental dynamic models for permeability studies

    • Authors: S. Scaglione, M.P. di Cagno
    • Year: Not specified
    • Citations: 0
  • 3D Bioprinting as a Powerful Technique for Recreating the Tumor Microenvironment

    • Authors: I. Parodi, D. Di Lisa, L. Pastorino, S. Scaglione, M.M. Fato
    • Year: 2023
    • Citations: 17
  • Different effects of NK cells and NK-derived soluble factors on cell lines derived from primary or metastatic pancreatic cancers

    • Authors: P.F. Fiore, A.L. Di Pace, L.A. Conti, L. Moretta, P. Vacca, et al.
    • Year: 2023
    • Citations: 5
  • A Human Ovarian Tumor & Liver Organ-on-Chip for Simultaneous and More Predictive Toxo-Efficacy Assays

    • Authors: A. Fedi, C. Vitale, M.M. Fato, S. Scaglione
    • Year: 2023
    • Citations: 10
  • Mathematical model of nutrients transport and cell growth in a bioprinted hydrogel

    • Authors: I. Parodi, S. Scaglione, M.M. Fato, R. Repetto
    • Year: Not specified
    • Citations: 0

 

Melika Mirghaffari | Materials Science | Best Researcher Award

Ms. Melika Mirghaffari | Materials Science | Best Researcher Award

student at Department of biomedical engineering,science and research branch, islamic azad university, tehran,iran

Melika Mirghaffari is a dedicated researcher in biomedical engineering, specializing in regenerative medicine and advanced biomaterials. Currently pursuing her Bachelor of Science at Islamic Azad University, she has contributed to multiple research publications on piezoelectric scaffolds for bone and skin regeneration. With hands-on experience as a research assistant at ZhinoGene Research Services Co. and a medical imaging technician at Sana Nuclear Medicine Center, she combines theoretical knowledge with practical expertise. Proficient in Python, AI, and scientific tools like Mendeley and Biorender, she excels in research, proposal writing, and article publishing. Her multilingual abilities in Persian, Azerbaijani, English, and French further enhance her global research collaborations. Passionate about scientific advancements, she has presented on wound healing technologies and continues to expand her research footprint. With a strong academic record and a multidisciplinary skill set, she is a promising young researcher making valuable contributions to biomedical engineering.

Professional Profile 

Education

Melika Mirghaffari is currently pursuing a Bachelor of Science in Biomedical Engineering at Islamic Azad University, Science and Research Branch, Tehran, Iran (2020–2025). Her academic journey reflects a strong foundation in mathematics, physics, and natural sciences, having completed her High School Diploma in Mathematics and Physics at Farzanegan 6 High School, Tehran (2019–2020). Prior to that, she studied Natural Sciences at Farzanegan 6 High School, Tehran (2018–2019) and Farzanegan High School, Marand (2017–2018). Her educational background has provided her with a solid understanding of scientific principles, allowing her to engage in advanced research on biomaterials and regenerative medicine. Throughout her studies, she has demonstrated a keen interest in scientific research, developing skills in Python, AI, lab techniques, and medical imaging. With a strong academic foundation and hands-on research experience, she continues to expand her expertise in biomedical engineering, contributing to innovative advancements in the field.

Professional Experience

Melika Mirghaffari has gained extensive professional experience in biomedical research and medical imaging. Since October 2024, she has been working as a Research Assistant at ZhinoGene Research Services Co., contributing to cutting-edge studies in regenerative medicine and biomaterials. Additionally, she has been actively involved at Sana Nuclear Medicine Center since July 2020, where she currently serves as a Gamma Camera SPECT Medical Imaging Technician Assistant, gaining hands-on experience in diagnostic imaging and nuclear medicine. Previously, she worked as a Secretary at the same center from June 2020 to 2021. Her research involvement extends beyond lab work; in 2024, she presented on “Wound Healing Latest Advancements” in a Cell Therapy Course at ACECR, YARA, Tehran. With expertise in medical imaging, lab techniques, and biomedical engineering, Melika combines technical proficiency with research acumen, making significant contributions to her field at an early stage in her career.

Research Interest

Melika Mirghaffari’s research interests lie at the intersection of biomedical engineering, regenerative medicine, and biomaterials, with a particular focus on piezoelectric scaffolds, tissue engineering, and medical imaging. She is passionate about developing advanced biomaterials for bone and skin tissue regeneration, utilizing piezoelectric properties to enhance self-powered electrical stimulation for improved healing. Her work explores the application of electrospun nanofibers, 3D-printed biodegradable scaffolds, and hydrophilic coatings in medical devices. Additionally, she is interested in the integration of AI and computational modeling in biomedical research to optimize material properties for enhanced clinical applications. With hands-on experience in both experimental research and medical imaging, she aims to bridge the gap between engineering innovations and clinical applications. Through her research, she aspires to contribute to the development of next-generation biomaterials and regenerative therapies, improving patient outcomes and advancing the field of biomedical engineering.

Award and Honor

As a promising young researcher in biomedical engineering, Melika Mirghaffari has been recognized for her contributions to regenerative medicine and biomaterials research. Her dedication to scientific innovation and academic excellence has earned her opportunities to present her research, such as her 2024 presentation on “Wound Healing Latest Advancements” at the Cell Therapy Course, ACECR, YARA, Tehran. Additionally, her published and under-review research papers in renowned scientific journals highlight her contributions to piezoelectric scaffolds, bone regeneration, and biomaterial advancements. While early in her academic career, her work has positioned her as a strong candidate for prestigious awards in biomedical research. With her growing portfolio of scientific publications, research assistantship, and medical imaging expertise, she is poised to receive further recognition for her achievements. As she continues her research and innovation in biomedical engineering, she aims to earn distinctions in both national and international scientific communities.

Research Skill

Melika Mirghaffari possesses a diverse set of research skills that span biomedical engineering, biomaterials, and regenerative medicine. She is proficient in scientific research methodologies, literature review, and experimental design, enabling her to contribute to cutting-edge advancements in tissue engineering. Her expertise includes working with electrospun nanofibers, 3D-printed biodegradable scaffolds, and piezoelectric materials for bone and skin regeneration. Additionally, she is skilled in Python programming, AI applications, and computational modeling, which she integrates into her research for data analysis and simulation. She is experienced in writing research proposals, publishing scientific articles, and utilizing tools like Mendeley, Biorender, and Cell Designer for data organization and visualization. Her lab skills in medical imaging, biomaterial synthesis, and diagnostic techniques further enhance her research capabilities. With a strong foundation in both theoretical and practical biomedical research, she continues to refine her skills to contribute to innovative healthcare solutions.

Conclusion

Melika Mirghaffari exhibits strong research potential with significant contributions to biomedical engineering, especially in regenerative medicine. Her technical expertise, publication record, and interdisciplinary skills make her a worthy candidate for the Best Researcher Award. However, pursuing further academic qualifications and increasing first-author contributions could strengthen her profile even more.

Publications Top Noted

Title: Electro-spun Piezoelectric PLLA Smart Composites as a Scaffold on Bone Fracture: A Review
Authors: Melika Mirghaffari, Asal Mahmoodiyan, Shahram Mahboubizadeh, Atefeh Shahbazi, Yaser Soleimani, Sana Mirghaffari, Zahra Shahravi
Year: 2025
Citation: Mirghaffari, M., Mahmoodiyan, A., Mahboubizadeh, S., Shahbazi, A., Soleimani, Y., Mirghaffari, S., & Shahravi, Z. (2025). Electro-spun piezoelectric PLLA smart composites as a scaffold on bone fracture: A review. Regenerative Therapy, 2025-03. DOI: 10.1016/j.reth.2025.01.026.