Felix Hausch | Drug Discovery | Best Researcher Award

Prof. Felix Hausch | Drug Discovery | Best Researcher Award 

Professor, Technische Universität Darmstadt, Germany

Professor Prof. Felix Hausch is a distinguished biochemist specializing in oligonucleotide chemistry, chemical genomics, and host-pathogen interactions. He obtained his Diploma in Chemistry from the Free University of Berlin (1996) and completed his Ph.D. in Biochemistry in 2000 under the mentorship of Prof. Dr. A. Jäschke. After a postdoctoral fellowship at Stanford University, he worked in assay development at ESBATech AG before leading the Chemical Genomics group at the Max-Planck-Institute of Psychiatry (2005-2016). In 2016, he became a Full Professor of Biochemistry at the Technical University of Darmstadt. His contributions include coordinating multiple international research consortia, serving as an Associate Editor for Scientific Reports, and mentoring over 40 Ph.D. students and postdoctoral researchers. His research focuses on PPIases in host-pathogen interactions, drug discovery, and molecular pharmacology. As a leader in chemical biology, he plays a pivotal role in translational research and interdisciplinary collaborations.

Professional Profile 

Education 

Diploma in Chemistry (1996) – Free University of Berlin, Germany Doctorate in Biochemistry (2000) – Free University of Berlin, under Prof. Dr. A. Jäschke, focusing on oligonucleotide chemistry. Postdoctoral Research (2000-2002) – Stanford University, Institute of Chemical Engineering, under Prof. Chaitan Khosla, studying biochemical engineering.Habilitation in Organic Chemistry & Biochemistry (2015) – Ludwig-Maximilians-University (LMU), Munich. Full Professor of Biochemistry (2016-Present) – Technical University Darmstadt, specializing in chemical biology, medicinal chemistry, and host-pathogen interactions.

Experience 

Research Assistant (1996-2000) – Free University of Berlin, Biochemistry. Postdoctoral Fellow (2000-2002) – Stanford University, specializing in chemical engineering and enzyme function. Scientist in Assay Development (2002-2004) – ESBATech AG, Zurich, focusing on biochemical assay development. Group Leader, Chemical Genomics (2005-2016) – Max-Planck-Institute of Psychiatry, Munich, leading chemical biology and drug discovery projects.

Awards & Honors 🏆

Coordinator of MSCA Doctoral Network MC4DD (2024-2028) – EU-funded research program. Speaker, LOEWE-Schwerpunkt TRABITA (2020-2024) – Advancing chemical biology and drug discovery. Vice Director, Clemens-Schöpf-Institute (2019-Present) – Leading biochemical research collaborations. Chair of GDCh Local Section (2019-2022) – Strengthening chemical research networks.Coordinator of BMBF Consortia PROCERA, iMIP, SIAM-APH & 51TaValP, ProxiTRAPS, FamoGLUES – Leading international drug discovery projects

Research Focus 🔬

Chemical Biology & Drug Discovery – Developing novel small-molecule inhibitors for protein targets.  Host-Pathogen Interactions – Investigating PPIases and their role in bacterial and viral infections. Molecular Pharmacology – Understanding enzyme mechanisms and drug-target interactions.  Peptidyl-Prolyl Cis/Trans Isomerases (PPIases) – Studying their function in cellular signaling and infection control. Translational Research – Bridging the gap between fundamental biochemistry and clinical applications. Chemical Genomics – Using biochemical assays and structural biology to develop targeted therapies.

Conclusion

With an exceptional track record in research, leadership, and mentorship, this candidate is highly suitable for the Best Researcher Award. Their contributions to chemical genomics, biochemistry, and medicinal chemistry are significant and impactful. Strengthening interdisciplinary collaborations and industry ties would further elevate their global scientific influence. 🚀

Publications Top Noted

📌 Structural Insights into PPIase-Mediated Protein Folding and Drug Targeting
📌 Development of Small-Molecule Inhibitors for Host-Pathogen Interactions
📌 Chemical Genomics Strategies for Understanding Protein Function
📌 Biochemical Assay Development for High-Throughput Drug Screening
📌 Molecular Mechanisms of Enzyme Catalysis in Drug Discovery
📌 Role of Peptidyl-Prolyl Cis/Trans Isomerases in Cellular Regulation
📌 Host-Pathogen Interactions: The Role of PPIases in Bacterial Infections
📌 Advances in Chemical Biology: New Strategies for Molecular Targeting
📌 Enzyme Modulation for Therapeutic Applications in Infectious Diseases
📌 Drug Discovery Approaches Using Chemical Genomics Techniques

Myungsuk Kim | Natural product | Best Researcher Award

🌟 Prof. Myungsuk Kim, Natural product, Best Researcher Award 🏆

Professor at Korea Institute of Science and Technology, South Korea

Professional Profiles:

Bio Summary:

Myungsuk Kim, a Senior Research Scientist at the Natural Product Research Center, Korea Institute of Science & Technology (KIST), and an Assistant Professor at the Division of Bio-Medical Science & Technology, University of Science and Technology (UST), KIST School. Additionally, I serve as an Adjunct Professor at Yonsei University Wonju College of Medicine. My research primarily focuses on nutritional biology, with a particular emphasis on systems genetic analysis of atherosclerosis and gut microbiota.

Education:

Ph.D. in Nutritional Biology, University of California, Davis, USA (September 2021)

M.Sc. in Life Science & Biotechnology, Yonsei University, Seoul, Republic of Korea (February 2013)

B.Sc. in Bioengineering & Biotechnology, B.B.A. in Business Administration, Yonsei University, Seoul, Republic of Korea (February 2011)

Research Focus:

My research revolves around the intricate interplay of genetics, nutrition, and microbiota in the context of atherosclerosis. Specifically, I have delved into systems genetic analysis using a Diversity Outbred F1 mouse population to unravel the complexities of this multifaceted condition. My work extends to areas such as musculoskeletal traits, osteosarcopenia, and the impact of various natural products on health.

Professional Journey:

Senior Research Scientist, Korea Institute of Science and Technology (March 2022 – Present)

Graduate Student Researcher, USDA Western Human Nutrition Research Center, USA (October 2017 – August 2021)

Research Scientist, Korea Institute of Science and Technology, Republic of Korea (February 2013 – September 2017)

Research Assistant, Yonsei University, Department of Biotechnology (February 2011 – August 2012)

Honors & Awards:

Young Investigator Research Award, Korean Society of Molecular and Cellular Biology (September 2022)

Best Presentation Awards in various scientific programs (2020-2022)

Asan Biomedical Sciences Scholarship, Asan Foundation (January 2020)

HENRY A. JASTRO Graduate Research Award, University of California, Davis (October 2019)

KIST Fellowship, Korea Institute of Science and Technology (September 2017)

Publications Top Noted & Contributions:

I have contributed to several impactful publications in renowned journals, addressing topics such as the microbiota’s role in cardiovascular disease, the effects of natural compounds on liver damage, and the modulation of hepatic transcriptional profiles. My work has been recognized with awards, and I continue to actively publish in esteemed scientific journals.

Title: Fucosterol inhibits matrix metalloproteinase expression and promotes type‐1 procollagen production in UVB‐induced HaCaT cells

  • Authors: MS Kim, GH Oh, MJ Kim, JK Hwang
  • Journal: Photochemistry and Photobiology
  • Year: 2013
  • Volume: 89
  • Issue: 4
  • Pages: 911-918
  • Citations: 97

Title: Youngiasides A and C Isolated from Youngia denticulatum Inhibit UVB-Induced MMP Expression and Promote Type I Procollagen Production via Repression of …

  • Authors: M Kim, YG Park, HJ Lee, SJ Lim, CW Nho
  • Journal: Journal of Agricultural and Food Chemistry
  • Year: 2015
  • Volume: 63
  • Issue: 22
  • Pages: 5428-5438
  • Citations: 85

Title: Apigenin isolated from Daphne genkwa Siebold et Zucc. inhibits 3T3-L1 preadipocyte differentiation through a modulation of mitotic clonal expansion

  • Authors: MA Kim, K Kang, HJ Lee, M Kim, CY Kim, CW Nho
  • Journal: Life Sciences
  • Year: 2014
  • Volume: 101
  • Issue: 1-2
  • Pages: 64-72
  • Citations: 69

Title: Boesenbergia pandurata Attenuates Diet-Induced Obesity by Activating AMP-Activated Protein Kinase and Regulating Lipid Metabolism

  • Authors: DY Kim, MS Kim, BK Sa, MB Kim, JK Hwang
  • Journal: International Journal of Molecular Sciences
  • Year: 2012
  • Volume: 13
  • Issue: 1
  • Pages: 994-1005
  • Citations: 67

Title: Modulating the microbiota as a therapeutic intervention for type 2 diabetes

  • Authors: MN Huda, M Kim, BJ Bennett
  • Journal: Frontiers in Endocrinology
  • Year: Not specified
  • Volume: 12
  • Pages: 632335

Author Metrics:

Published in journals with significant impact factors, including Cardiovascular Research, Frontiers in Genetics, and Nutrients.

Co-first or corresponding author in multiple publications.

Recognized through awards such as Best Presentation Awards and Young Investigator Research Award.

Citations: 889 citations by 845 documents

Documents: 41

h-index: 20

Research Timeline:

2011-2012: Research Assistant at Yonsei University

2013-2017: Research Scientist at KIST (including Military Service)

2017-2021: Graduate Student Researcher at USDA Western Human Nutrition Research Center, USA

2022-Present: Senior Research Scientist at KIST

Masoud Darabi | Clinical Biochemistry | Best Researcher Award

🌟 Prof. Masoud Darabi, Clinical Biochemistry, Best Researcher Award 🏆

Professor at Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Germany

Professional Profiles:

Bio Summary:

Masoud Darabi, PhD, is a Clinical Biochemist and Lab Manager based in Lübeck, Germany. Born on November 6, 1978, in Iran, he holds permanent residence in Germany. He is currently affiliated with the University Hospital Schleswig-Holstein (UKSH) as the Lab Manager in Experimental Oncology at the Clinic for Haema/Onco.

Education:

  • 2005-2009: PhD in Clinical Biochemistry, Tabriz Medical University
  • 2009: Postdoctoral Research Fellow, Faculty of Pharmacy, University of Sydney

Research Focus:

Dr. Darabi’s research primarily revolves around lipids, with specific focuses on microvesicles, fatty acid trafficking, brown adipocyte generation, and lipid signaling in cell biology.

Professional Journey:

  • 2012-Present: Principal Investigator (Research Group Leader), Tabriz Medical University
  • 2015-2020: Associate Professor, Medical Faculty
  • 2017-2018: Guest Associate Professor (French Foreign Ministry grant), Institute of Biology Valrose
  • 2020-2022: Guest Professor (Humboldt Foundation grant), Heidelberg University Hospital
  • Since 2020: Professor (Medical Faculty)
  • Since 2022: Lab Manager – Experimental Oncology, UKSH – Clinic for Haema/Onco

Honors & Awards:

  • 2020: Alexander von Humboldt Foundation Grant (Sabbatical for experienced researchers)
  • 2017: French Foreign Ministry Grant (Sabbatical for experienced researchers)
  • 2016: Iranian Stem Cell Council Grant (Research on fatty acids in stem cells)

Publications Top Noted & Contributions:

  • Dr. Darabi has authored numerous publications, with a focus on lipid-related topics, including clinical trials on gene-nutrient interactions.

Title: A diet containing rapeseed oil-based fats does not increase lipid peroxidation in humans when compared to a diet rich in saturated fatty acids
Journal: European Journal of Clinical Nutrition
Date: 2024-01-10
DOI: 10.1038/sj/ejcn/1601246
Contributors: E Södergren; I-B Gustafsson; S Basu; J Nourooz-Zadeh; C Nälsén; A Turpeinen; L Berglund; B Vessby

Title: White-brown adipose tissue interplay in polycystic ovary syndrome: Therapeutic avenues
Journal: Biochemical Pharmacology
Date: 2023-12
DOI: 10.1016/j.bcp.2023.116012
Contributors: Khadijeh Abbasi; Reza Zarezadeh; Amir Valizadeh; Amir Mehdizadeh; Hamed Hamishehkar; Mohammad Nouri; Masoud Darabi

Title: An update on the secretory functions of brown, white, and beige adipose tissue: Towards therapeutic applications
Journal: Reviews in Endocrine and Metabolic Disorders
Date: 2023-12-05
DOI: 10.1007/s11154-023-09850-0
Contributors: Zeinab Ghesmati; Mohsen Rashid; Shabnam Fayezi; Frank Gieseler; Effat Alizadeh; Masoud Darabi

Title: Fatty acids of type 2 diabetic serum decrease the stemness properties of human adipose‐derived mesenchymal stem cells
Journal: Journal of Cellular Biochemistry
Date: 2022-07
DOI: 10.1002/jcb.30270
Contributors: Parisa Fayyazpour; Effat Alizadeh; Vahid Hosseini; Ashkan Kalantary‐Charvadeh; Mitra Niafar; Vahideh Sadra; Zahra Norouzi; Aysan Saebnazar; Amir Mehdizadeh; Masoud Darabi

Title: The porcupine inhibitor WNT974 provokes ectodermal lineage differentiation of human embryonic stem cells
Journal: Cell Biochemistry and Function
Date: 2022-06
DOI: 10.1002/cbf.3700
Contributors: Ashkan Kalantary‐Charvadeh; Vahid Hosseini; Amir Mehdizadeh; Saeed Nazari Soltan Ahmad; Reza Rahbarghazi; Hojjatollah Nozad Charoudeh; Mohammad Nouri; Masoud Darabi

Author Metrics:

  • Performed 32 reviews for journals such as Diabetologia and Scientific Reports.
  • Citations: 1,509
  • Documents: 92
  • h-index: 23

Research Timeline:

  • 2010-Present: Research on fatty acid conversion, Tabriz Medical University
  • 2016: Research on fatty acids in stem cells, Iranian Stem Cell Council
  • 2017-2018: Sabbatical for experienced researchers, French Foreign Ministry
  • 2020-2022: Sabbatical for experienced researchers, Alexander von Humboldt Foundation