Associate Professor of Medical Microbiology & Immunology at Management and Science University, Malaysia
Assoc. Prof. Dr. Mohammed AbdelFatah Mosa Al-Hoot is an accomplished academic and researcher in Medical Microbiology and Immunology, specializing in Virology and Molecular Microbiology. With a career spanning over two decades, he has made significant contributions to molecular virology, antiviral therapeutics, antimicrobial resistance, nanoparticle-based treatments, and infectious diseases. His research on dengue virus inhibition through siRNA and antiviral peptides, as well as nanoparticle antibacterials and phytochemical antiviral screening, has been widely recognized. He has authored more than 40 peer-reviewed publications, contributed book chapters, and holds a patent, with his work attracting over 600 citations globally. A leader in postgraduate supervision, curriculum development, and research ethics, Dr. Al-Hoot also serves as an editor and reviewer for international journals. His collaborative projects across countries, commitment to capacity building, and contributions to scientific knowledge have positioned him as a respected figure in the global research community.
Professional Profile
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Education
Dr. Al-Hoot’s academic journey reflects a strong foundation in medical sciences and research excellence. He earned his Bachelor’s degree with honors in Medical Laboratory Sciences, followed by a Master’s in Microbiology, both of which equipped him with essential skills in laboratory diagnostics and infectious disease analysis. Building on this expertise, he pursued and completed a Ph.D. in Medical Microbiology, specializing in Medical Virology, at a leading university. His doctoral research focused on innovative antiviral strategies, laying the groundwork for his subsequent contributions to molecular virology and translational therapeutics. Throughout his education, Dr. Al-Hoot consistently demonstrated academic distinction, earning scholarships and recognition for his scholarly performance. His academic qualifications have provided a strong platform for his research in virology, antimicrobial resistance, and nanoparticle therapeutics, enabling him to bridge fundamental science with applied biomedical solutions. His education has also shaped his teaching and mentorship, fostering future leaders in the microbiology and biomedical fields.
Experience
Dr. Al-Hoot’s professional career spans extensive academic, research, and clinical laboratory roles, reflecting his versatility and leadership in medical microbiology. He has served as an Associate Professor at a reputed Malaysian university, where he has been actively involved in teaching, research supervision, curriculum coordination, and academic leadership. His experience includes managing and leading numerous research projects, both as principal investigator and collaborator, with international partners. Over the years, he has successfully supervised numerous Ph.D. and Master’s students to completion, contributing to global research capacity building. His professional journey also encompasses significant editorial and peer review responsibilities for high-impact scientific journals, ensuring the quality of published research in his field. In addition to his academic work, he has engaged in community outreach, research ethics committees, and scientific event organization. This multifaceted experience underscores his ability to integrate research, teaching, and service for impactful contributions to science and society.
Research Interest
Dr. Al-Hoot’s research interests lie at the intersection of molecular virology, antimicrobial resistance, and innovative therapeutic approaches. He focuses on developing antiviral strategies targeting viral entry and replication, particularly for dengue virus and other significant pathogens. His work explores the use of small interfering RNA (siRNA), synthetic antiviral peptides, and natural products as novel therapeutics. Additionally, he investigates nanoparticle-based antibacterial agents and their role in combating drug-resistant microorganisms. His interests also extend to diagnostic microbiology, infectious diseases, and gut microbiota modulation. By integrating molecular biology techniques with translational applications, Dr. Al-Hoot aims to address global health challenges through innovative, sustainable, and effective solutions. His interdisciplinary research approach fosters collaboration between microbiology, nanotechnology, pharmacology, and clinical sciences, ensuring that his work remains relevant to both scientific advancement and public health needs. These interests continue to guide his projects, publications, and mentorship of emerging researchers in the field.
Awards and Honors
Dr. Al-Hoot’s excellence in research and academia has been recognized through numerous awards and honors. He has received the University of Malaya Excellence Award for his outstanding contributions to scientific research, as well as prestigious scholarships, including the MIS Scholarship during his doctoral studies. His institution has honored him with multiple service excellence recognitions, acknowledging his dedication to teaching, research, and community service. He has been invited as a keynote speaker and panelist at international conferences, reflecting the high regard for his expertise in virology and antimicrobial research. His editorial roles in globally recognized journals and active involvement in peer review further underscore his professional standing. Additionally, his contributions to collaborative projects and research ethics committees have earned him respect within the academic community. These accolades not only celebrate his past achievements but also highlight his continuing commitment to advancing microbiology and immunology for societal benefit.
Research Skills
Dr. Al-Hoot possesses a diverse and advanced skill set in medical microbiology, molecular virology, and infectious disease research. His technical expertise includes RNA interference, synthetic antiviral peptide development, nanoparticle synthesis for antimicrobial applications, molecular diagnostics, and advanced microbiological assays. He is proficient in designing and conducting translational research studies that bridge laboratory findings to clinical applications. His skills extend to grant writing, securing competitive funding, and leading multi-institutional and international research collaborations. In the academic sphere, he excels in curriculum design, postgraduate supervision, and mentorship, fostering the next generation of researchers. His editorial and peer-review experience with high-impact journals demonstrates his ability to critically evaluate scientific work and maintain research integrity. Additionally, his involvement in organizing scientific conferences and workshops highlights his capabilities in knowledge dissemination and community engagement. Collectively, these skills enable him to contribute significantly to both scientific discovery and the broader biomedical research ecosystem.
Publications Top Notes
Title: Autophagy and Senescence: A New Insight in Selected Human Diseases
Authors: P. Rajendran, A.M. Alzahrani, H.N. Hanieh, S.A. Kumar, R. Ben Ammar, M.A. Alhoot, and others
Year: 2019
Citations: 128
Title: Inhibition of Dengue Virus Entry into Target Cells Using Synthetic Antiviral Peptides
Authors: M.A. Alhoot, A.K. Rathinam, S.M. Wang, R. Manikam, S.D. Sekaran
Year: 2013
Citations: 83
Title: Inhibition of Dengue Virus Entry and Multiplication into Monocytes Using RNA Interference
Authors: M.A. Alhoot, S.M. Wang, S.D. Sekaran
Year: 2011
Citations: 70
Title: RNA Interference Mediated Inhibition of Dengue Virus Multiplication and Entry in HepG2 Cells
Authors: M.A. Alhoot, S.M. Wang, S.D. Sekaran
Year: 2012
Citations: 66
Title: Isolation and Screening of Extracellular Protease Enzyme from Fungal Isolates of Soil
Authors: A.M.A. Maitig, M.A.M. Alhoot, K. Tiwari
Year: 2018
Citations: 50
Title: Genetic Diversity of Fungi Producing Mycotoxins in Stored Crops
Authors: F.E.M. Eltariki, K. Tiwari, I.A. Ariffin, M.A. Alhoot
Year: 2018
Citations: 23
Title: An Association between Khat and Diabetes
Authors: A.M. El Hadrani, M.A. Alhoot
Year: 2000
Citations: 23
Title: Climate Change and Health: The Malaysia Scenario
Authors: M.A. Alhoot, W.T. Tong, W.Y. Low, S.D. Sekaran
Year: 2016
Citations: 21
Conclusion
Assoc. Prof. Dr. Mohammed AbdelFatah Mosa Al-Hoot is a distinguished scientist in Medical Microbiology and Immunology, with specialization in Virology and Molecular Microbiology. His research covers molecular virology, antiviral therapeutics, antimicrobial resistance, nanoparticle-based treatments, and infectious diseases, with notable work on dengue virus inhibition through siRNA and antiviral peptides, as well as nanoparticle antibacterials and phytochemical antiviral screening. He holds advanced degrees in medical microbiology and has extensive academic and clinical experience, contributing significantly to education and research. He has led and collaborated on multiple funded projects across several countries, producing over 40 peer-reviewed publications, book chapters, and a patent, with substantial citations. Serving as an editor and reviewer for international journals, he actively advances research quality. His leadership includes curriculum development, postgraduate supervision, ethics committee service, and organizing academic events. Dedicated to mentorship, collaboration, and innovation, he has made impactful contributions to science, capacity building, and the global research community.
