Mahnaz Ghaebi | Immunology | Best Researcher Award

Ms. Mahnaz Ghaebi | Immunology | Best Researcher Award

Prospective PhD Student | Zanjan University of Medical Sciences | Iran

Dr. Mahnaz Ghaebi is a medical immunologist and researcher with strong expertise in regenerative medicine, nanotechnology, immunoengineering, biosensors, micro/nanofluidics, and biomaterials. She earned her B.Sc. in Biology from Zanjan University in 2012, graduating as valedictorian and ranked first in her cohort, followed by an M.Sc. in Medical Immunology from Tabriz University of Medical Sciences in 2018, where she completed her thesis on the frequency and epigenetic factors of Treg, Th17, and exhausted T cells in recurrent implantation failure patients. She has enriched her academic training through a Research Internship Course in Pharmaceutical Bioengineering in 2024, covering stem cell design, protein/enzyme engineering, microbial bioengineering, and vaccine design. Professionally, Dr. Ghaebi has served as a Research Assistant at Zanjan University of Medical Sciences (2023–2024), Laboratory Technician during the COVID-19 pandemic, Teaching Assistant guiding students in immunological protocols, and Research Assistant at Tabriz University of Medical Sciences, where she gained hands-on expertise in molecular and cellular biology techniques, flow cytometry, ELISA, and quantitative PCR. Her research interests bridge basic and applied biomedical sciences, with skills extending to bioinformatics, vaccine design, protein modeling, transcriptomic analysis, and computational tools such as R, Python, and Chimera. She has co-authored a book chapter in Springer’s Handbook of Cancer and Immunology and published in reputed journals including Biomedicine & Pharmacotherapy, while also serving as a peer reviewer for international journals such as Survey of Ophthalmology, International Journal of Rheumatic Diseases, and GeroScience. Dr. Ghaebi’s dedication has been recognized with multiple honors, including academic excellence awards, ranking among the top 30 in Iran’s National Entrance Exam for M.Sc., and receiving letters of appreciation for her volunteer leadership during the COVID-19 crisis. Her scholarly contributions reflect growing international recognition, with 1,032 citations by 918 documents, 20 publications, and an h-index of 16.

Profiles: Google Scholar | Scopus | ORCID

Featured Publications

  1. Valizadeh, H., Abdolmohammadi-Vahid, S., Danshina, S., Gencer, M. Z., … & Ghaebi, M. (2020). Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients. International Immunopharmacology, 89, 107088. Cited by: 306

  2. Ghaebi, M., Nouri, M., Ghasemzadeh, A., Farzadi, L., Jadidi-Niaragh, F., Ahmadi, M., … & Yousefi, M. (2017). Immune regulatory network in successful pregnancy and reproductive failures. Biomedicine & Pharmacotherapy, 88, 61–73. Cited by: 173

  3. Tahmasebi, S., Qasim, M. T., Krivenkova, M. V., Zekiy, A. O., Thangavelu, L., … & Ghaebi, M. (2021). The effects of oxygen–ozone therapy on regulatory T‐cell responses in multiple sclerosis patients. Cell Biology International, 45(7), 1498–1509. Cited by: 170

  4. Ahmadi, M., Abdolmohammadi-Vahid, S., Ghaebi, M., Aghebati-Maleki, L., Afkham, A., Danaii, S., … & Yousefi, M. (2017). Effect of intravenous immunoglobulin on Th1 and Th2 lymphocytes and improvement of pregnancy outcome in recurrent pregnancy loss (RPL). Biomedicine & Pharmacotherapy, 92, 1095–1102. Cited by: 103

  5. Ghaebi, M., Osali, A., Valizadeh, H., Roshangar, L., & Ahmadi, M. (2020). Vaccine development and therapeutic design for 2019‐nCoV/SARS‐CoV‐2: Challenges and chances. Journal of Cellular Physiology, 235(12), 9098–9109. Cited by: 86

Hua Jin | Immunology and Microbiology | Best Researcher Award

Ms. Hua Jin | Immunology and Microbiology | Best Researcher Award

Research Assistant at Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, China

Ms. Hua Jin is a highly accomplished researcher in hepatology and immunology. She holds an M.B. in clinical medicine and advanced degrees (M.S. and M.D.) in hepatology from Capital Medical University and Beijing Friendship Hospital, China. Currently, she works as a researcher at the Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital. Her research focuses on liver injury and immune responses, particularly the role of OX40 in hepatic ischemia-reperfusion injury and drug-induced liver damage. She has co-authored numerous high-impact publications in journals like JCI Insight, British Journal of Pharmacology, and Cell Reports. Her groundbreaking work has earned her recognition, including the prestigious American Transplant Congress Young Investigator Award in 2021. In addition to her research, she has presented her findings at major international conferences, including the Asian Pacific Association for the Study of the Liver and the American Transplant Congress.

Professional Profile

Education

Ms. Hua Jin has a strong academic background in clinical medicine and hepatology. She completed her undergraduate studies in Clinical Medicine at Chongqing Medical University in China, earning her M.B. degree from 2009 to 2014. Following this, she pursued advanced training in hepatology, earning her M.S. degree from the Experimental and Translational Research Center at Beijing Friendship Hospital, Capital Medical University, from 2015 to 2018. Building on this foundation, she furthered her expertise by obtaining an M.D. in hepatology, also from the Experimental and Translational Research Center, between 2018 and 2021. This rigorous education provided Ms. Jin with a deep understanding of both clinical and research aspects of hepatology, setting the stage for her current work in immunology and liver disease. Her academic achievements reflect a commitment to advancing knowledge in medical research, particularly in the areas of liver injury and immune system regulation.

Professional Experience

Ms. Hua Jin has extensive professional experience in the field of medical research, particularly in hepatology and immunology. After completing her advanced degrees, she began her research career as a Research Assistant at the Immunology Research Center for Oral and Systemic Health at Beijing Friendship Hospital, Capital Medical University, from 2021 to 2024. During this time, she worked on critical research related to immune responses in liver injury, with a focus on the role of OX40 in liver diseases. In 2024, she transitioned to her current role at the Medical Research Center, Beijing Institute of Respiratory Medicine, and Beijing Chao-Yang Hospital, where she continues her work in hepatology and immunology. Throughout her career, Ms. Jin has contributed to numerous high-impact research projects, authored multiple publications in prestigious journals, and presented her work at leading international conferences, establishing herself as a promising young investigator in the field of liver disease and immune system regulation.

Research interest

Ms. Hua Jin’s research interests primarily focus on hepatology, immunology, and liver diseases. Her work investigates the immune mechanisms underlying liver injury, particularly the role of immune checkpoints like OX40 in hepatic ischemia-reperfusion injury, drug-induced liver injury, and non-alcoholic steatohepatitis (NASH). She is particularly interested in how immune responses, both innate and adaptive, contribute to liver diseases, aiming to identify potential therapeutic targets for improving liver function and preventing damage. Her research also delves into the cellular and molecular dynamics of immune cells such as neutrophils and T cells in liver injury. Through the application of advanced techniques like single-cell transcriptomics, she explores the heterogeneity of immune cell populations and their roles in inflammation and liver repair. Ms. Jin’s work seeks to bridge the gap between basic immunology and clinical hepatology, with the goal of developing novel, immune-based therapeutic strategies for liver diseases.

Award and Honor

Ms. Hua Jin has received notable recognition for her research contributions, highlighting her prominence in the fields of hepatology and immunology. In 2021, she was honored with the prestigious American Transplant Congress Young Investigator Award, which acknowledges exceptional young researchers making significant strides in transplant medicine and immunology. This award reflects the high regard her work has garnered within the scientific community. Additionally, Ms. Jin has published multiple influential papers in top-tier journals, such as JCI Insight, Cell Reports, and British Journal of Pharmacology, further cementing her status as a rising star in medical research. Her innovative studies on immune responses in liver injury and the role of immune checkpoints like OX40 have gained widespread recognition. Furthermore, she has presented her research at prominent international conferences, including the Asian Pacific Association for the Study of the Liver and American Transplant Congress, showcasing her contributions to the global medical research community.

Conclusion

Hua Jin demonstrates the core qualities of an outstanding researcher: academic excellence, groundbreaking contributions, and recognition within his field. His work on immune responses in liver injury is cutting-edge and contributes valuable insights to the medical community. With continued growth in his research portfolio and a potential increase in his mentorship and international networking, he could further enhance his impact. Based on these strengths, Hua Jin is highly deserving of consideration for the Best Researcher Award.

Publications Top Noted

  • “Rebalancing liver-infiltrating CCR3+ and CD206+ monocytes improves diet-induced NAFLD”
    • Authors: Sun, G., Wang, Y., Yang, L., Zhang, Z., Zhang, D.
    • Year: 2023
    • Citations: 5
  • Erratum to “Isolation and purification of immune cells from the liver”
    • Authors: Shi, W., Wang, Y., Zhang, C., Zhang, D., Sun, G.
    • Year: 2023
    • Citations: 0
  • “OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis”
    • Authors: Xu, L., Tian, D., Zhou, M., Zhang, D., Wu, J.
    • Year: 2022
    • Citations: 2
  • “Reciprocal alterations in circulating and hepatic gamma–delta T cells in patients with primary biliary cholangitis”
    • Authors: Chen, S., Lv, T., Sun, G., Zhang, D., Jia, J.
    • Year: 2022
    • Citations: 6
  • “The Critical and Diverse Roles of CD4–CD8– Double Negative T Cells in Nonalcoholic Fatty Liver Disease”
    • Authors: Li, C., Du, X., Shen, Z., Zhang, D., Sun, G.
    • Year: 2022
    • Citations: 11
  • “CD4 derived double negative T cells prevent the development and progression of nonalcoholic steatohepatitis”
    • Authors: Sun, G., Zhao, X., Li, M., Zhang, Z., Zhang, D.
    • Year: 2021
    • Citations: 22
  • “Transcriptome landscape of double negative T cells by single-cell RNA sequencing”
    • Authors: Yang, L., Zhu, Y., Tian, D., Zhao, Y., Zhang, D.
    • Year: 2021
    • Citations: 26
  • “Dietary Inorganic Nitrate Protects Hepatic Ischemia-Reperfusion Injury Through NRF2-Mediated Antioxidative Stress”
    • Authors: Li, S., Jin, H., Sun, G., Zhang, D., Wang, S.
    • Year: 2021
    • Citations: 14
  • “Isolation and purification of immune cells from the liver”
    • Authors: Shi, W., Wang, Y., Zhang, C., Zhang, D., Sun, G.
    • Year: 2020
    • Citations: 34
  • “Critical role of OX40 in drug-induced acute liver injury”
    • Authors: Zhang, C., Jin, H., Wang, Y., Sun, G., Zhang, D.
    • Year: 2020
    • Citations: 4

 

Shanaz sharaf | Immunology and histopathology | Best Researcher Award

Mrs. Shanaz sharaf | Immunology and histopathology | Best Researcher Award

PhD Scholar of Regional Cancer Centre, India

Mrs. Shanaz Sharaf is a dedicated researcher with 7 years of experience in biotechnology, biomedical sciences, cell and molecular biology, and clinical research. 🎓 Her work primarily focuses on understanding prognostic tumor markers in Triple Negative Breast Cancer (TNBC), exploring molecular and cell signaling aspects in tumorigenesis, and developing innovative technologies for cancer detection. 🧬 Passionate about advancing cancer research, Mrs. Sharaf is committed to creating novel multiplex technologies for tumor tissue imaging. She aims to leverage her skills and knowledge in a collaborative environment to contribute to cutting-edge scientific advancements and gain exposure to emerging technologies. 🌟

Professional profile

Education📚

Mrs. Shanaz Sharaf holds a Doctor of Philosophy (Ph.D.) in Biotechnology from Manipal Academy of Higher Education, India, where she conducted research on prognostic markers and multiplex platforms for breast cancer classification. 📚 Her academic journey includes a Master of Science in Biotechnology from the University of Kerala, graduating with first-class honors and a distinction of 75.05%. 🎓 Prior to that, she earned a Bachelor of Science in Botany and Biotechnology from the University of Kerala, also with first-class honors and a notable 74.05%. 🌟 Her educational background equips her with a strong foundation in biotechnological and biomedical sciences, essential for her research endeavors.

Professional Experience🏛️

Mrs. Shanaz Sharaf brings a wealth of experience to her field, having served as a PhD Scholar at the Regional Cancer Centre, Thiruvananthapuram, Kerala, India, from 2019 to 2024. 🎓 Her research focused on identifying prognostic markers and developing multiplex platforms for breast cancer classification under the guidance of Dr. K Sujathan. 🧬 Prior to her PhD, she worked as a Junior Research Fellow on translational research in Triple Negative Breast Cancer (2017-2019) and investigated maternal sleep deprivation effects on offspring cognition (2014-2015) at SCTIMST, Thiruvananthapuram. 🔬 Her extensive research background showcases her expertise in molecular and cell biology, particularly in cancer research and innovative diagnostic techniques. 🧪

Research Interest🌐

Mrs. Shanaz Sharaf’s research interests lie in the intersection of biotechnology and cancer research. 🔬 Her primary focus is on understanding the role of prognostic tumor markers in Triple Negative Breast Cancer (TNBC), aiming to enhance disease outcome predictions and improve detection methods. 🧬 She explores various molecular and cell signaling pathways involved in tumorigenesis and is passionate about developing novel multiplex technologies for tumor tissue imaging. 🧪 Her work seeks to innovate cancer detection and treatment, leveraging cutting-edge techniques to advance the field of oncology. 🌟

Awards and Honors🏆

Mrs. Shanaz Sharaf has received notable recognition for her contributions to cancer research and biotechnology. 🏅 Her commitment to advancing the field has been acknowledged through various awards and honors. 🎖️ These accolades highlight her innovative work and dedication, reflecting her impact on the scientific community and her role in pioneering new approaches to cancer detection and treatment. 🌟 Her achievements underscore her excellence and commitment to improving health outcomes through research and innovation. 🌺

Achievements🏅
  • 🎓 Doctoral Research: Completed a Ph.D. in Biotechnology at Manipal Academy of Higher Education, focusing on identifying prognostic markers and developing multiplex platforms for breast cancer classification.
  • 🧬 Research Contributions: Significant work in Triple Negative Breast Cancer, including translational research and novel strategies in cancer detection.
  • 🔬 Conference Organization: Actively involved in organizing major conferences like the Indo-Swedish Conference on Analytical Cell Biology and Machine Learning in Cancer Research (2019) and the National Conference on ETHB (2023).
  • 📚 Research Experience: Junior Research Fellow (JRF) with projects on maternal sleep deprivation effects and translational research in breast cancer.
  • 🏆 Professional Recognition: Contributed to significant research advancements and gained recognition within the scientific community for her innovative approaches and findings.
  • 💡 Innovative Technologies: Development of innovative multiplex technologies for tumor tissue imaging, enhancing cancer research methodologies.
Projects🛠️
  • 🔍 Prognostic Markers in Breast Cancer: Identified a panel of prognostic markers and developed a multiplex platform for histoclinical classification of breast cancer during her Ph.D. research at the Regional Cancer Centre.
  • 🧬 Triple Negative Breast Cancer: Conducted translational research focusing on the role of various prognostic tumor markers in Triple Negative Breast Cancer.
  • 🧪 Maternal Sleep Deprivation Study: Investigated the effects of maternal sleep deprivation on cognition in offspring using an animal model during her tenure as a Junior Research Fellow.
  • 🧩 Tumor Tissue Imaging: Worked on developing innovative multiplex technologies for enhanced imaging of tumor tissues.
  • 🗂️ Conference Organization: Played a key role in organizing major conferences, including the Indo-Swedish Conference on Analytical Cell Biology and Machine Learning in Cancer Research and the National Conference on ETHB.
Publications top noted📜
  • 📄 “Subcellular expression of MTA1, HIF1A, and p53 in primary tumor predicts aggressive triple negative breast cancers: a meta-analysis based study”
    • Authors: Sharaf, S.S., Jaganath Krishna, K.M., Lekshmi, A., Sujathan
    • Journal: Journal of Molecular Histology
    • Year: 2024
    • Volume: 55
    • Issue: 3
    • Pages: 303–315
    • Citations: 0
  • 📄 “A multiplex immunoprofiling approach for detecting the co-localization of breast cancer biomarkers using a combination of Alexafluor – Quantum dot conjugates and a panel of chromogenic dyes”
    • Authors: Sharaf, S.S., Lekshmi, A., S, A., Santhosh Kumar, T.R., K, S.
    • Journal: Pathology Research and Practice
    • Year: 2024
    • Volume: 253
    • Article: 155033
    • Citations: 1