Virologo molecolare at INMI L Spallanzani IRCCS Rome, Italy
Dr. Anna Rosa Garbuglia, born on August 2, 1963, is an esteemed Italian biologist specializing in virology and microbiology. Currently serving as a Dirigente Biologo I livello at the Istituto Nazionale per le Malattie Infettive “L. Spallanzani” I.R.C.C.S., she has been a pivotal figure in the field since her appointment in 1991. Her career spans extensive research in viral infections, including hepatitis B, C, and HIV, with significant contributions to understanding viral pathogenesis and developing diagnostic techniques. Dr. Garbuglia is also recognized for her leadership in various research projects and collaborations, contributing to advancements in molecular epidemiology and vaccine research.
Publication Profile
Google Scholar
Education
Dr. Garbuglia earned her Laurea in Scienze Biologiche from the University of Florence in 1987, graduating with honors. She continued her studies with a Diploma di Specializzazione in Microbiologia e Virologia from “La Sapienza” University in 1998, and a Laurea in Farmacia from the University of Camerino in 1994. Her academic journey further includes a Master in Bioetica and a subsequent Licenza in Bioetica from the Pontifical Regina Apostolorum University in 2003 and 2007, respectively. These qualifications underscore her extensive expertise in biological sciences and ethics.
Experience
Dr. Garbuglia has held various prestigious roles since 1991, beginning as a Dirigente Biologo at Ospedale S. Camillo, later integrated into IRCCS INMI “L. Spallanzani”. Her responsibilities have included leadership in virology diagnostics and biosafety. Notable positions include being responsible for the epatiti research line, and serving as acting Director of the UOC Virology and Biosafety Laboratories. Her career reflects a robust involvement in both administrative and research roles, particularly focusing on advanced diagnostics and epidemiological research.
Research Focus
Dr. Garbuglia’s research primarily delves into viral interactions and pathogenesis, notably in hepatitis B (HBV), C (HCV), and HIV. She investigates viral evolution, immune responses, and diagnostic methodologies. Recent studies include HPV-related cancer research and the effectiveness of therapeutic vaccines. Her work on HCV involves epidemiological studies and drug resistance, while her contributions to SARS-CoV-2 research focus on immune responses to different virus variants. Her research aims to enhance diagnostic techniques and therapeutic strategies for viral infections.
Publications Top Notes
- Epidemiological, clinical and virological characteristics of four cases of monkeypox support transmission through sexual contact, Italy, May 2022
Antinori A., Mazzotta V., Vita S., Carletti F., Tacconi D., Lapini LE, …
Eurosurveillance 27 (22), 2200421
🗓️ 2022 | 📊 563 citations
- Grossly Defective nef Gene Sequences in a Human Immunodeficiency Virus Type 1-Seropositive Long-Term Nonprogressor
Salvi R., Garbuglia AR., Di Caro A., Pulciani S., Montella F., Benedetto A.
Journal of Virology 72 (5), 3646-3657
🗓️ 1998 | 📊 257 citations
- HIV-particles in spermatozoa of patients with AIDS and their transfer into the oocyte
Baccetti B., Benedetto A., Burrini AG., Collodel G., Ceccarini EC., Crisà N., …
The Journal of Cell Biology 127 (4), 903-914
🗓️ 1994 | 📊 227 citations
- Monkeypox virus isolation from a semen sample collected in the early phase of infection in a patient with prolonged seminal viral shedding
Lapa D., Carletti F., Mazzotta V., Matusali G., Pinnetti C., Meschi S., …
The Lancet Infectious Diseases 22 (9), 1267-1269
🗓️ 2022 | 📊 208 citations
- The use of both therapeutic and prophylactic vaccines in the therapy of papillomavirus disease
Garbuglia AR., Lapa D., Sias C., Capobianchi MR., Del Porto P.
Frontiers in Immunology 11, 188
🗓️ 2020 | 📊 153 citations
- Epidemiology of hepatitis E virus in European countries
Lapa D., Capobianchi MR., Garbuglia AR.
International Journal of Molecular Sciences 16 (10), 25711-25743
🗓️ 2015 | 📊 150 citations
- Hepatitis E virus genotype 4 outbreak, Italy, 2011
Garbuglia AR., Scognamiglio P., Petrosillo N., Mastroianni CM., Sordillo P., …
Emerging Infectious Diseases 19 (1), 110
🗓️ 2013 | 📊 122 citations
- Multispecific T cell response and negative HCV RNA tests during acute HCV infection are early prognostic factors of spontaneous clearance
Spada E., Mele A., Berton A., Ruggeri L., Ferrigno L., Garbuglia AR., …
Gut 53 (11), 1673-1681
🗓️ 2004 | 📊 115 citations
- Early impairment of hepatitis C virus-specific T cell proliferation during acute infection leads to failure of viral clearance
Folgori A., Spada E., Pezzanera M., Ruggeri L., Mele A., Garbuglia AR., …
Gut 55 (7), 1012-1019
🗓️ 2006 | 📊 109 citations
- Factors predicting the persistence of genital human papillomavirus infections and PAP smear abnormality in HIV-positive and HIV-negative women during prospective follow-up
Branca M., Garbuglia AR., Benedetto A., Cappiello T., Leoncini L., Migliore G., …
International Journal of STD & AIDS 14 (6), 417-425
🗓️ 2003 | 📊 94 citations
- Detection of TT virus in lymph node biopsies of B-cell lymphoma and Hodgkin’s disease, and its association with EBV infection
Garbuglia AR., Iezzi T., Capobianchi MR., Pignoloni P., Pulsoni A., Sourdis J., …
International Journal of Immunopathology and Pharmacology 16 (2), 109-118
🗓️ 2003 | 📊 94 citations
- Hepatitis E virus in Italy: molecular analysis of travel-related and autochthonous cases
La Rosa G., Muscillo M., Vennarucci VS., Garbuglia AR., La Scala P., …
Journal of General Virology 92 (7), 1617-1626
🗓️ 2011 | 📊 91 citations
- The debate on the presence of HIV-1 in human gametes
Baccetti B., Benedetto A., Collodel G., Di Caro A., Garbuglia AR., Piomboni P.
Journal of Reproductive Immunology 41 (1-2), 41-67
🗓️ 1998 | 📊 81 citations
- Immunogenicity to COVID-19 mRNA vaccine third dose in people living with HIV
Vergori A., Cozzi Lepri A., Cicalini S., Matusali G., Bordoni V., Lanini S., …
Nature Communications 13 (1), 4922
🗓️ 2022 | 📊 78 citations
- Positive selection of cytotoxic T lymphocyte escape variants during acute hepatitis C virus infection
Guglietta S., Garbuglia AR., Pacciani V., Scottà C., Perrone MP., Laurenti L., …
European Journal of Immunology 35 (9), 2627-2637
🗓️ 2005 | 📊 72 citations
