Bio Summary:
Dr. Yi-Ying Chiou is currently an Assistant Professor at the Graduate Institute of Biochemistry, National Chung Hsing University in Taiwan. With a Ph.D. in Biopharmaceutical Sciences, her research focuses on circadian biology, DNA damage repair, and the molecular mechanisms governing the circadian clock. Dr. Chiou has an extensive academic background and has held postdoctoral positions at renowned institutions, including the University of North Carolina at Chapel Hill.
Education:
B.Sc. in Life Sciences, National Yang-Ming University, Taiwan (1999-2003)
Ph.D. in Biopharmaceutical Sciences, National Yang-Ming University, Taiwan (2004-2011)
Research Focus:
Dr. Chiou’s primary research interests include circadian modulation of cellular processes, DNA damage repair mechanisms, and the interplay between circadian clock components. Her work involves understanding the molecular basis of circadian rhythms and their impact on cellular functions, with a focus on the transcription-translation feedback loop.
Professional Journey:
Assistant Professor, Graduate Institute of Biochemistry, National Chung Hsing University, Taiwan (2017 – Present)
Postdoctoral Fellow, Aziz Sancar Lab, Biochemistry and Biophysics Department, University of North Carolina at Chapel Hill, U.S.A (2012 – 2017)
Postdoctoral Fellow, Faculty of Life Sciences, School of Life Science, National Yang-Ming University, Taiwan (2011 – 2012)
Publications Top Noted & Contributions:
Dr. Chiou has made significant contributions to the field, publishing research articles in reputable scientific journals. Her work spans topics such as circadian clock regulation, DNA damage repair, and molecular mechanisms of cellular processes. Notable publications include:
Title: Dual modes of CLOCK: BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock
- Authors: R Ye, CP Selby, YY Chiou, I Ozkan-Dagliyan, S Gaddameedhi, A Sancar
- Journal: Genes & development
- Year: 2014
- Cited By: 230
- Title: Circadian clock, cancer, and chemotherapy
Authors: A Sancar, LA Lindsey-Boltz, S Gaddameedhi, CP Selby, R Ye, YY Chiou, …
- Journal: Biochemistry
- Year: 2015
- Cited By: 165
Title: Mammalian Period represses and de-represses transcription by displacing CLOCK–BMAL1 from promoters in a Cryptochrome-dependent manner
- Authors: YY Chiou, Y Yang, N Rashid, R Ye, CP Selby, A Sancar
- Journal: Proceedings of the National Academy of Sciences
- Year: 2016
- Cited By: 141
Title: Cisplatin-DNA adduct repair of transcribed genes is controlled by two circadian programs in mouse tissues
- Authors: Y Yang, O Adebali, G Wu, CP Selby, YY Chiou, N Rashid, J Hu, …
- Journal: Proceedings of the National Academy of Sciences
- Year: 2018
- Cited By: 91
Title: Human genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo [a] pyrene
- Authors: W Li, J Hu, O Adebali, S Adar, Y Yang, YY Chiou, A Sancar
- Journal: Proceedings of the National Academy of Sciences
- Year: 2017
Author Metrics:
Citations: 1144
h-index: 13
i10-index: 15
Research Timeline:
2017 – Present: Assistant Professor, National Chung Hsing University, Taiwan
2012 – 2017: Postdoctoral Fellow, University of North Carolina at Chapel Hill, U.S.A
2011 – 2012: Postdoctoral Fellow, National Yang-Ming University, Taiwan
2004 – 2011: Ph.D., National Yang-Ming University, Taiwan
1999 – 2003: B.Sc., National Yang-Ming University, Taiwan
