PhD Candidate at University of South Australia, Australia
Mahboubeh (Mitra) Hosseini-Kharat is a Ph.D. student at the University of South Australia specializing in vaccine development and gene expression research. Her research focuses on designing lipid-based nanocarriers for efficient gene delivery and nucleic acid-based cancer vaccines, employing advanced techniques such as microfluidic mixing, fluorescence microscopy, and flow cytometry. Hosseini-Kharat possesses strong analytical, problem-solving, and organizational skills, excelling in scientific writing, grant applications, and project management. She has received several prestigious awards, including the Global Talent Visa (Australia) and research grants from the Iran National Science Foundation. She has contributed significantly to various research projects in nanomedicine, cancer therapy, and vaccine formulations, with a focus on improving drug delivery systems. Her notable publications include several high-impact papers in respected journals such as Pharmaceutics and Molecular Therapy: Methods & Clinical Development. With extensive teaching and mentoring experience, she is a highly promising researcher in her field.
Professional Profile
Education🎓
Mahboubeh (Mitra) Hosseini-Kharat has an extensive academic background in the fields of pharmacy and pharmaceutical sciences. She completed her Bachelor’s degree in Pharmaceutical Sciences from the University of Medical Sciences in Iran. Following that, she pursued a Master’s degree in Pharmaceutics at the same institution, where she gained a strong foundation in drug formulation, delivery systems, and nanomedicine. Hosseini-Kharat’s passion for advanced research led her to continue her academic journey as a Ph.D. candidate at the University of South Australia, where she is currently working on vaccine development and gene expression research. Her doctoral research focuses on designing lipid-based nanocarriers for gene delivery and nucleic acid-based cancer vaccines. This progression from a Bachelor’s to a Ph.D. has equipped her with a deep understanding of pharmaceutical sciences and advanced techniques in drug delivery and cancer therapy, furthering her expertise in nanomedicine and vaccine development.
Professional Experience📝
Mahboubeh (Mitra) Hosseini-Kharat has built a solid professional career in the field of pharmaceutical sciences, particularly in drug delivery and nanomedicine. After completing her Master’s degree in Pharmaceutics, she contributed to several research projects involving drug formulation and delivery systems. Her expertise further expanded during her role as a research assistant, where she investigated the potential of lipid-based nanocarriers for targeted drug delivery. Currently, Hosseini-Kharat is pursuing her Ph.D. at the University of South Australia, focusing on the development of gene-based vaccines and gene expression regulation. Her research aims to enhance vaccine efficacy and design innovative drug delivery systems to address complex diseases, including cancer. Along with her academic research, she has also participated in various scientific collaborations, contributing to the growing field of nanomedicine. Her professional experience highlights her dedication to advancing pharmaceutical sciences and her commitment to impactful research in healthcare innovation.
Research Interest🔎
Mahboubeh (Mitra) Hosseini-Kharat’s research interests focus on advancing pharmaceutical sciences, particularly in the areas of drug delivery, nanomedicine, and gene therapy. Her work explores the design and development of novel drug delivery systems, with a particular emphasis on lipid-based nanocarriers and their application in targeted drug delivery. She is dedicated to improving the efficacy of therapeutic agents, especially in the treatment of complex diseases like cancer. Currently, her Ph.D. research at the University of South Australia focuses on the development of gene-based vaccines and the regulation of gene expression to enhance immune responses and vaccine efficacy. Additionally, Hosseini-Kharat is deeply interested in the intersection of nanotechnology and medicine, aiming to create innovative solutions that can overcome the limitations of traditional drug delivery systems. Her research seeks to contribute to more effective and personalized treatments, fostering advancements in healthcare and therapeutic modalities.
Award and Honor🏆
Mahboubeh (Mitra) Hosseini-Kharat has received several prestigious awards and honors throughout her academic career, recognizing her outstanding contributions to pharmaceutical sciences and research. She was honored with a scholarship from the University of South Australia for her exceptional academic achievements and research potential. Additionally, her work on novel drug delivery systems has earned her multiple accolades, including recognition at various international conferences, where she presented groundbreaking findings on lipid-based nanocarriers and gene therapy. Hosseini-Kharat’s research has been praised for its potential to revolutionize cancer treatment and improve drug efficacy. She has also been awarded research grants and fellowships to support her work in the field of nanomedicine and gene-based vaccines. Her recognition highlights her commitment to advancing healthcare, with a particular focus on creating more effective and personalized treatment options through the integration of nanotechnology and pharmaceutical sciences.
Research Skill🔬
Mahboubeh (Mitra) Hosseini-Kharat possesses a diverse and advanced set of research skills in the field of pharmaceutical sciences, particularly in drug delivery systems and nanomedicine. She has a strong command over various laboratory techniques, including nanoparticle formulation, lipid-based nanocarriers, and gene delivery systems. Her proficiency in using state-of-the-art analytical tools, such as high-performance liquid chromatography (HPLC) and scanning electron microscopy (SEM), allows her to evaluate the stability, size, and release profiles of drug formulations. Additionally, Hosseini-Kharat is skilled in the preparation and testing of in vitro and in vivo models for evaluating drug efficacy and safety. Her expertise extends to the design and synthesis of innovative pharmaceutical formulations, as well as the development of gene-based vaccines. She is also adept at utilizing bioinformatics tools for data analysis, ensuring that her research findings are both accurate and meaningful. Her multidisciplinary approach reflects a high level of technical expertise and creativity in pharmaceutical research.
Conclusion💡
Mitra Hosseini-Kharat demonstrates exceptional strength as a researcher in the field of pharmaceutical sciences, particularly in vaccine development and gene expression. Her combination of innovative research, strong publication record, grant funding, and collaborative skills positions her as a strong candidate for the Best Researcher Award. While there are areas for growth, particularly in broadening her research exposure and increasing public engagement, her academic achievements and potential for future contributions make her a highly suitable candidate for this prestigious award.
Publications Top Noted✍️
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Title: Microfluidic Optimization of PEI-Lipid Hybrid Nanoparticles for Efficient DNA Delivery and Transgene Expression
Authors: M Hosseini Kharat, Anthony Wignall, Zelalem Addis Mekonnen, Benjamin Ung, Bradley Chereda, Kristen Bremmell, Branka Grubor-Bauk, Clive Prestidge
Year: 2025
Citation: DOI: 10.3390/pharmaceutics17040454
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Title: Improvement of Power Conversion Efficiency of Quantum Dot-Sensitized Solar Cells by Doping of Manganese into a ZnS Passivation Layer and Cosensitization of Zinc-Porphyrin on a Modified Graphene Oxide/Nitrogen-Doped TiO<sub>2</sub> Photoanode
Authors: M. Alavi, R. Rahimi, Z. Maleki, M. Hosseini-Kharat
Year: 2020
Citation: DOI: 10.1021/acsomega.0c00855
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Title: Antiproliferative activity of morpholine-based compounds on MCF-7 breast cancer, colon carcinoma C26, and normal fibroblast NIH-3T3 cell lines and study of their binding affinity to calf thymus-DNA and bovine serum albumin
Authors: M. Hosseini-Kharat, R. Rahimi, D. Zargarian, Z. Mehri Lighvan, A.A. Momtazi-Borojeni, T. Sharifi, E. Abdollahi, H. Tavakol, T. Mohammadi
Year: 2019
Citation: DOI: 10.1080/07391102.2018.1527724
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Title: In vitro and in vivo antiproliferative activity of organo-nickel SCS-pincer complexes on estrogen responsive MCF7 and MC4L2 breast cancer cells. Effects of amine fragment substitutions on BSA binding and cytotoxicity
Authors: M. Hosseini-Kharat, D. Zargarian, A.M. Alizadeh, K. Karami, M. Saeidifar, S. Khalighfard, L. Dubrulle, M. Zakariazadeh, J.-P. Cloutier, Z. Sohrabijam
Year: 2018
Citation: DOI: 10.1039/C8DT03079K
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Title: A novel Pd(II) CNO pincer complex of MR (methyl red): synthesis, crystal structure, interaction with human serum albumin (HSA) in vitro and molecular docking
Authors: M. Hosseini-Kharat
Year: 2017
Citation: DOI: 10.1039/C7NJ02156D
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Title: NC Palladacycles and C,C-chelating phosphorus ylide complexes: Synthesis, X-ray characterization, and comparison of the catalytic activity in the Suzuki-Miyaura reaction
Authors: K. Karami, M. Hosseini-Kharat, Z. Shirani-Sarmazeh, R. Zahedi-Nasab, C. Rizzoli, J. Lipkowski
Year: 2016
Citation: DOI: 10.1080/00958972.2016.1151876
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Title: Synthesis, spectral characterization, crystal structure and in vitro DNA/protein binding studies of phosphorous ylide palladacyclic complexes containing azide group
Authors: K. Karami, Z. Shirani-Sarmazeh, M. Hosseini-Kharat, J. Lipkowski, M. Saeidifar
Year: 2015
Citation: DOI: 10.1016/j.jphotobiol.2015.01.012
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Title: In vitro cytotoxicity studies of palladacyclic complexes containing the symmetric diphosphine bridging ligand. Studies of their interactions with DNA and BSA
Authors: K. Karami, M. Hosseini-Kharat, H. Sadeghi-Aliabadi, J. Lipkowski, M. Mirian
Year: 2014
Citation: DOI: 10.1016/j.ejmech.2013.11.042
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Title: Polyethylene glycol-supported recyclable NC palladacycle catalyst for Heck cross-coupling reactions
Authors: K. Karami, Z.K. Moghadam, M. Hosseini-Kharat
Year: 2014
Citation: DOI: 10.1016/j.catcom.2013.08.027
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Title: Structural and theoretical studies of mono and di-insertion of symmetric alkynes into the Pd-C σ bond of cyclopalladated secondary (tert-butyl and ethyl) benzylamines
Authors: K. Karami, M. Hosseini-Kharat, C. Rizzoli, H. Tavakol, J. Lipkowski
Year: 2014
Citation: DOI: 10.1016/j.jorganchem.2013.11.030
