Chief Scientific Officer at Pronokal Group, Spain
Dr. Luis Ignacio Sajoux Parrile is a distinguished clinical researcher and scientific leader with a strong focus on obesity, metabolic disorders, and ketogenic dietary interventions. Serving as Chief Scientific Officer and Scientific Director at Pronokal Group (a Nestlé Health Science company), he has led innovative research resulting in patented methodologies applied across 18 countries. With over a decade of experience, his work includes coordinating international clinical trials, advancing genomic-based treatments, and publishing in reputable journals such as Endocrine and Nutr Diabetes. Ranked among the most influential global authors in very low-calorie ketogenic diets (VLCKD), he holds an h-index of 13 and g-index of 19. Dr. Sajoux also founded the Neurometrics Institute, integrating neuroscience with nutrition and behavior research. His contributions extend to policy, strategic leadership, and international scientific collaboration. While further academic mentorship and recent publications could strengthen his profile, he is highly deserving of the Best Researcher Award.
Professional Profile
Education🎓
Dr. Luis Ignacio Sajoux Parrile holds a comprehensive and multidisciplinary educational background that bridges clinical medicine, surgery, business, and aesthetic science. He earned his medical degree from the University of Buenos Aires in 2003, followed by a General Surgery specialization completed at the French University Hospital in 2008. His academic path then expanded into healthcare management and innovation with an Executive MBA (EMBA) from ESADE Business School in 2017, one of Europe’s top institutions for business leadership. Further enhancing his clinical expertise, he completed a Master’s degree in Aesthetic Medicine at the University of Barcelona in 2022. This diverse educational foundation supports his ability to integrate medical science, clinical research, strategic management, and technological innovation. It has enabled him to lead complex research initiatives, oversee clinical trials, and develop patented methodologies in nutrition and obesity treatment across international settings. His academic trajectory reflects a strong commitment to lifelong learning and multidisciplinary excellence.
Professional Experience📝
Dr. Luis Ignacio Sajoux Parrile has built a dynamic professional career at the intersection of clinical medicine, scientific research, and corporate leadership. Beginning in Buenos Aires, he specialized in Digestive Surgery after earning his medical degree, then relocated to Barcelona to focus on obesity treatment and clinical research. Since 2010, he has served as Chief Scientific Officer at Pronokal Health Group, now part of Nestlé Health Science, where he has led numerous clinical trials and developed patented nutritional strategies implemented in over 18 countries. He also serves as Scientific Director of the Biobank Genomics and President of the Compliance Committee, guiding genomic-based obesity research and ethical oversight. In 2015, he founded the Neurometrics Institute, focusing on neurobehavioral research in obesity, ADHD, and autism. His work bridges clinical innovation, public health, and strategic corporate growth, including participation in corporate acquisitions and digital transformation, making him a recognized leader in evidence-based healthcare solutions.
Research Interest🔎
Dr. Luis Ignacio Sajoux Parrile’s research interests center on obesity management, metabolic health, ketogenic dietary therapies, and the integration of genomics and neuroscience in clinical practice. He is particularly recognized for his pioneering work on very low-calorie ketogenic diets (VLCKD), contributing to both the scientific understanding and clinical application of these interventions in treating obesity and type 2 diabetes. His research also explores the mechanisms of lipoinflammation, the impact of DHA supplementation, and the long-term effects of nutritional strategies on visceral fat reduction. Dr. Sajoux has expanded his focus to include neurocognitive development, especially in pediatric populations with conditions such as ADHD and autism, through protein-based nutritional interventions. He actively contributes to real-world clinical studies and the design of genomics-based personalized treatment plans. By combining clinical science with translational innovation, his work supports the development of multidisciplinary approaches to obesity and behavioral health, improving patient outcomes across diverse populations and healthcare systems.
Award and Honor🏆
Dr. Luis Ignacio Sajoux Parrile has earned recognition and honors for his significant contributions to clinical research, particularly in the field of obesity and ketogenic nutritional therapy. A recent bibliometric analysis published in Endocrine, Metabolic & Immune Disorders—Drug Targets ranked him among the most influential global authors in the field of very low-calorie ketogenic diets (VLCKD), underscoring his impact and leadership in this area. His patented nutritional methodologies are used across 18 countries, reflecting the international relevance and application of his innovations. As a respected figure in scientific and medical communities, he is frequently invited to speak at international congresses and symposia focused on obesity, metabolism, and nutritional science. Additionally, Dr. Sajoux has been instrumental in forming and leading expert panels, international boards, and clinical research collaborations. These roles demonstrate not only his scientific expertise but also his ability to influence healthcare practices and policies across borders through impactful, evidence-based contributions.
Research Skill🔬
Dr. Luis Ignacio Sajoux Parrile possesses a comprehensive set of research skills that span clinical trial design, epidemiological study coordination, biomedical innovation, and translational science. His expertise lies in developing and implementing real-world clinical studies, particularly in the areas of obesity, metabolic disorders, and ketogenic dietary interventions. He is skilled in leading multidisciplinary research teams, managing complex datasets, and applying systems biology approaches to understand the molecular mechanisms underlying nutritional therapies. Dr. Sajoux demonstrates strong analytical and problem-solving abilities, evident in his development of two patented nutritional methodologies currently applied in over 18 countries. His ability to bridge clinical research with genomic diagnostics enhances the personalization of treatment strategies. Additionally, his founding of the Neurometrics Institute highlights his proficiency in neurobehavioral research, particularly in populations with ADHD and autism. With experience in both corporate and academic environments, he excels in translating scientific findings into practical healthcare solutions with global impact.
Conclusion💡
Dr. Luis Ignacio Sajoux Parrile is highly suitable for the Best Researcher Award, particularly in the domain of obesity treatment, ketogenic dietary interventions, and clinical research innovation. His blend of scientific rigor, translational outcomes, and international recognition supports a compelling case for the award. While improvements in academic independence and broader research dissemination could further elevate his candidacy, his leadership and contributions already place him as a strong contender.
Publications Top Noted✍️
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Obesity-related osteopontin protein and methylation blood levels are differentially modulated by a very low-calorie ketogenic diet or bariatric surgery
Authors: Lorenzo, P.M.; Izquierdo, A.G.; Sajoux, I.; Nuñez-Garcia, M.; Gomez-Arbelaez, D.; Zulet, M.A.; Abete, I.; Baltar, J.; de Luis, D.; Tinahones, F.J.
Year: 2025
Citation: Clinical Nutrition (Edinburgh, Scotland), DOI: 10.1016/j.clnu.2025.02.006
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A very-low-calorie ketogenic diet normalises obesity-related enhanced levels of erythropoietin compared with a low-calorie diet or bariatric surgery
Authors: Fernandez-Pombo, A.; Lorenzo, P.M.; Carreira, M.C.; Gomez-Arbelaez, D.; Castro, A.I.; Primo, D.; Rodriguez, J.; Sajoux, I.; Baltar, J.; de Luis, D.
Year: 2024
Citation: Journal of Endocrinological Investigation, DOI: 10.1007/s40618-024-02364-9
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Does the Ketogenic Diet Mediate Inflammation Markers in Obese and Overweight Adults? A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Authors: Rondanelli, M.; Gasparri, C.; Pirola, M.; Barrile, G.C.; Moroni, A.; Sajoux, I.; Perna, S.
Year: 2024
Citation: Nutrients, DOI: 10.3390/nu16234002
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Efficacy of very low-calorie ketogenic diet with the Pronokal® method in obese women with polycystic ovary syndrome: a 16-week randomized controlled trial
Authors: Pandurevic, S.; Mancini, I.; Mitselman, D.; Magagnoli, M.; Teglia, R.; Fazzeri, R.; Dionese, P.; Cecchetti, C.; Caprio, M.; Moretti, C.; Sajoux, I.
Year: 2023
Citation: Endocrine Connections, DOI: 10.1530/ec-22-0536
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Very low calorie ketogenic diet and common rheumatic disorders: A case report
Authors: Rondanelli, M.; Patelli, Z.; Gasparri, C.; Mansueto, F.; Ferraris, C.; Nichetti, M.; Alalwan, T.A.; Sajoux, I.; Maugeri, R.; Perna, S.
Year: 2023
Citation: World Journal of Clinical Cases, DOI: 10.12998/wjcc.v11.i9.1985
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Immunomodulatory effect of a very-low-calorie ketogenic diet compared with bariatric surgery and a low-calorie diet in patients with excessive body weight
Authors: Lorenzo, P.M.; Sajoux, I.; Izquierdo, A.G.; Gomez-Arbelaez, D.; Zulet, M.A.; Abete, I.; Castro, A.I.; Baltar, J.; Portillo, M.P.; Tinahones, F.J.
Year: 2022
Citation: Clinical Nutrition (Edinburgh, Scotland), DOI: 10.1016/j.clnu.2022.05.007
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Severe type 2 diabetes (T2D) remission using a very low-calorie ketogenic diet (VLCKD)
Authors: Correa, L.L.; de Sousa, P.A.M.; Dinis, L.; Carloto, L.B.; Nuñez-Garcia, M.; Sajoux, I.; Senhorini, S.
Year: 2022
Citation: Endocrinology, Diabetes & Metabolism Case Reports, DOI: 10.1530/edm-22-0295
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Corrigendum: The Potential Roles of Very Low Calorie, Very Low Calorie Ketogenic Diets and Very Low Carbohydrate Diets on the Gut Microbiota Composition
Authors: Rondanelli, M.; Gasparri, C.; Peroni, G.; Faliva, M.A.; Naso, M.; Perna, S.; Bazire, P.; Sajoux, I.; Maugeri, R.; Rigon, C.
Year: 2021
Citation: Frontiers in Endocrinology, DOI: 10.3389/fendo.2021.825790
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Effectiveness and Safety of a Very Low-Calorie Ketogenic Diet on Weight Regain Following Bariatric Surgery
Authors: Correa, L.L.; Moretti, A.; de Sousa, P.A.M.; Dinis, L.; de Souza, M.F.; Tostes, I.; Nuñez-Garcia, M.; Sajoux, I.
Year: 2021
Citation: Obesity Surgery, DOI: 10.1007/s11695-021-05703-4
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Epigenetic landscape in blood leukocytes following ketosis and weight loss induced by a very low calorie ketogenic diet (VLCKD) in patients with obesity
Authors: Crujeiras, A.B.; Izquierdo, A.G.; Primo, D.; Milagro, F.I.; Sajoux, I.; Jácome, A.; Fernandez-Quintela, A.; Portillo, M.P.; Martínez, J.A.; Martinez-Olmos, M.A.
Year: 2021
Citation: Clinical Nutrition (Edinburgh, Scotland), DOI: 10.1016/j.clnu.2021.05.010
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Randomized Clinical Trial to Evaluate the Morphological Changes in the Adventitial Vasa Vasorum Density and Biological Markers of Endothelial Dysfunction in Subjects with Moderate Obesity Undergoing a Very Low-Calorie Ketogenic Diet
Authors: Sánchez, E.; Santos, M.D.; Nuñez-Garcia, M.; Bueno, M.; Sajoux, I.; Yeramian, A.; Lecube, A.
Year: 2021
Citation: Nutrients, DOI: 10.3390/nu14010033
