Dingan Zhou | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Prof. Dingan Zhou | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Assistant research fellow at Clinical Research Center at the Affiliated Hospital of Guizhou Medical University, China

Prof. Dingโ€™an Zhou is an esteemed researcher and associated research fellow at the Clinical Research Center of the Affiliated Hospital of Guizhou Medical University. He is also a postgraduate mentor at the School of Clinical Laboratory Science, Guizhou Medical University. ๐Ÿฅ๐ŸŽ“

Professional profile

Education๐Ÿ“š

Prof. Zhou earned his PhD in Biochemistry and Molecular Biology from Fudan University in Shanghai, China, in December 2012. His doctoral research focused on the causative genes and mechanisms of genetic diseases such as dyschromatosis universalis hereditarian (DUH) and autosomal dominant congenital cataract. ๐ŸŽ“๐Ÿ”ฌ

Professional Experience๐Ÿ›๏ธ

Following his PhD, Prof. Zhou worked as an Assistant Research Fellow at the First Affiliated Hospital of Chongqing Medical University starting in March 2013. His work there delved into the mechanisms underlying DUH phenotypes and the role of SASH1 as a tumor suppressor in breast cancer. In March 2017, he returned to Guiyang, his hometown, to join the Affiliated Hospital of Guizhou Medical University. ๐Ÿฅ๐Ÿ”

Research Interest๐ŸŒ

Prof. Zhou’s research interests are broad and include the identification of causative genes and mechanisms in rare genetic diseases, such as DUH, multiple endocrine neoplasia type 1 (MEN1), Retinitis Pigmentosa, 11 ฮฒ-hydroxylase deficiency (11ฮฒ-OHD), and Schmid type metaphyseal chondrodysplasia (SMCD). He is also focused on the post-translational modifications (phosphorylation and ubiquitylation) of key molecules in breast cancer. ๐Ÿงฌ๐Ÿ”ฌ

Awards and Honors๐Ÿ†

Prof. Zhou has been honored with the Thousand Talents Innovation Award under the Hundred Million Talent Introduction Plan of Guizhou Province. This prestigious award recognizes his significant contributions and innovations in his field. ๐Ÿ†๐ŸŒŸ

Achievements๐Ÿ…
  • PhD in Biochemistry and Molecular Biology: Awarded by Fudan University, focusing on genetic diseases such as dyschromatosis universalis hereditarian (DUH) and congenital cataract. ๐ŸŽ“๐Ÿ”ฌ
  • Research on DUH and Breast Cancer: Investigated mechanisms of DUH phenotypes and the role of SASH1 as a tumor suppressor in breast cancer during his tenure at the First Affiliated Hospital of Chongqing Medical University. ๐Ÿ”๐Ÿงฌ
  • Thousand Talents Innovation Award: Received the prestigious award under the Hundred Million Talent Introduction Plan of Guizhou Province, recognizing his impactful research and contributions. ๐Ÿ†๐ŸŒŸ
  • Broad Research Scope: Conducted extensive research on genetic diseases, including MEN1, Retinitis Pigmentosa, 11 ฮฒ-hydroxylase deficiency (11ฮฒ-OHD), and Schmid type metaphyseal chondrodysplasia (SMCD). ๐Ÿงฌ๐Ÿ”
  • Post-Translational Modification Studies: Explored phosphorylation and ubiquitylation modifications of key molecules in breast cancer, contributing valuable insights to cancer research. ๐Ÿงฌ๐Ÿ”ฌ
Publications top noted๐Ÿ“œ
  • “A novel genomic rearrangement on chr19q13.42 leads to PRPF31-associated retinitis pigmentosa”
    Authors: Lu, Q., Yang, J., Xiong, Y., Zhang, M., Zhou, D.
    Journal: Clinical and Experimental Ophthalmology, 2024, 52(5), pp. 595โ€“598
    Citations: 1 ๐Ÿ“–๐Ÿ”ฌ
  • “Blockade of a novel MAP4K4-LATS2-SASH1-YAP1 cascade inhibits tumorigenesis and metastasis in luminal breast cancer”
    Authors: Yang, P., Li, Y., Hou, J., Zeng, X., Zhou, D.
    Journal: Journal of Biological Chemistry, 2024, 300(6), 107309
    Citations: 0 ๐Ÿ“–๐Ÿšซ
  • “The circadian clock gene, BMAL1, promotes radiosensitization in nasopharyngeal carcinoma by inhibiting the epithelial-to-mesenchymal transition via the TGF-ฮฒ1/Smads/Snail1 axis”
    Authors: Li, Y., Zhou, Y., Zhao, C., Zhou, D., Jin, F.
    Journal: Oral Oncology, 2024, 152, 106798
    Citations: 2 ๐Ÿ“–๐ŸŒŸ
  • “Dickkopf-1 is an immune infiltration-related prognostic biomarker of head and neck squamous cell carcinoma”
    Authors: Zhao, C., Liu, L., He, Q., Zhou, D., Jin, F.
    Journal: Aging, 2024, 16(4), pp. 3837โ€“3855
    Citations: 1 ๐Ÿ“–๐Ÿ”ฌ
  • “Unequal crossing over between CYP11B2 and CYP11B1 causes 11 ฮฒ -hydroxylase deficiency in a consanguineous family”
    Authors: Xiong, Y., Zeng, Z., Liang, T., Zhang, M., Zhou, D.
    Journal: Journal of Steroid Biochemistry and Molecular Biology, 2023, 233, 106375
    Citations: 5 ๐Ÿ“–๐ŸŒŸ
  • “Retyping and molecular pathology diagnosis of dyschromatosis universalis hereditaria”
    Authors: Zhou, D., Yang, P., Chen, H.
    Journal: Experimental Dermatology, 2023, 32(9), pp. 1334โ€“1343
    Citations: 1 ๐Ÿ“–๐Ÿ”ฌ
  • “The PER3 rs772027021 SNP induces pigmentation phenotypes of dyschromatosis universalis hereditaria”
    Authors: Chen, H., Yang, P., Yang, D., Xing, Q., Zhou, D.
    Journal: Journal of Molecular Medicine, 2023, 101(3), pp. 279โ€“294
    Citations: 3 ๐Ÿ“–๐Ÿ”ฌ
  • “The biological clock gene BMAL1 inhibits the proliferation, migration and invasion of radiation-resistant nasopharyngeal carcinoma cell line 5-8FR by regulating PI3K/Akt/MMP-2/9 signaling pathway”
    Authors: Li, Y., Zhao, C., Liu, L., Zhou, J., Jin, F.
    Journal: Chinese Journal of Radiation Oncology, 2022, 31(11), pp. 1039โ€“1045
    Citations: 0 ๐Ÿ“–๐Ÿšซ
  • “Association between platelets and in-hospital mortality in critically ill patients with tumours: a retrospective cohort study”
    Authors: Zhao, C., Qin, Z., Tang, Y., Zhou, D., Jin, F.
    Journal: BMJ Open, 2022, 12(4), e053691
    Citations: 1 ๐Ÿ“–๐Ÿ”ฌ

Wang Wu | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Assoc. Prof. Dr. Wang Wu | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Associate Professor of College of Bioengineering, Chongqing University, China

Wang Wu is a dedicated researcher specializing in dermal adipocyte regeneration and wound repair. With a robust academic background, Wang completed postdoctoral research at Chongqing University (06/2021 – 11/2023) and pursued doctoral studies at Sun Yat-sen University (06/2018 – 08/2018). Wang holds a Masterโ€™s degree from Beihua University (09/2015 – 06/2018) and a Bachelorโ€™s degree from Hubei University for Nationalities (09/2009 – 06/2015). Wangโ€™s research has garnered significant support through prestigious grants, including those from the National Natural Science Foundation of China and the National Key Research and Development Program of China. Wangโ€™s work is instrumental in advancing our understanding and treatment of wound healing and adipocyte function, contributing to innovative solutions in medical science. ๐ŸŒŸ๐Ÿ”ฌ๐Ÿ’‰

Professional profile

Education๐Ÿ“š

Wang Wu has a distinguished academic background with extensive training in the field of biomedical research. Wang completed a Postdoctoral Fellowship at Chongqing University (06/2021 – 11/2023), where advanced studies in dermal adipocyte regeneration and wound repair were undertaken. Prior to this, Wang earned a Doctoral Degree from Sun Yat-sen University (06/2018 – 08/2018). Wangโ€™s foundational education includes a Masterโ€™s Degree from Beihua University (09/2015 – 06/2018) and a Bachelorโ€™s Degree from Hubei University for Nationalities (09/2009 – 06/2015). This comprehensive education has equipped Wang with a deep understanding of cellular biology and regenerative medicine, paving the way for impactful research and innovation in the field. ๐Ÿ“š๐Ÿ”ฌ๐Ÿ…

Professional Experience๐Ÿ›๏ธ

Wang Wu has a robust professional background in biomedical research. From June 2021 to November 2023, Wang served as a Postdoctoral Researcher at Chongqing University, focusing on dermal adipocyte regeneration and wound repair. This role involved groundbreaking research funded by prominent organizations such as the National Natural Science Foundation of China and the Chongqing Natural Science Foundation. Wangโ€™s previous experience includes significant contributions to key projects during their tenure as a Doctoral Researcher at Sun Yat-sen University and work as a Masterโ€™s Researcher at Beihua University. This extensive experience highlights Wangโ€™s expertise in innovative research, project management, and application of cutting-edge techniques in regenerative medicine. ๐Ÿงช๐Ÿ”ฌ๐Ÿ”

Research Interest๐ŸŒ

Wang Wu is deeply engaged in exploring dermal adipocyte regeneration and wound repair. Their research focuses on understanding the mechanisms behind skin cell regeneration and developing novel strategies to enhance wound healing. With a keen interest in biomedical advancements, Wang aims to unravel how dermal adipocytes contribute to tissue repair and regeneration. Their work involves leveraging fundamental research and applying insights from various funding programs such as the National Key Research and Development Program of China. This dedication to advancing regenerative medicine and innovative therapies underscores Wang Wu’s commitment to improving patient outcomes and developing cutting-edge solutions in the field. ๐Ÿงฌ๐Ÿฉบ๐ŸŒŸ

Awards and Honors๐Ÿ†

Wang Wu has been recognized for outstanding contributions to the field of biomedical research through several prestigious awards and honors. They have received support from the National Natural Science Foundation of China and the Chongqing Natural Science Foundation, underscoring their impactful work on dermal adipocyte regeneration and wound repair. Additionally, Wang was selected for the Chongqing Medical Talents: Exceptional Young Talents Project, reflecting their significant potential and achievements in medical science. Their research has also been supported by the National Key Research and Development Program of China and the Fundamental Research Funds for the Central Universities, highlighting their role in advancing knowledge and innovation in regenerative medicine. ๐Ÿฅ‡๐ŸŽ“๐ŸŒŸ

Achievements๐Ÿ…
  • Research Excellence: Secured funding from the National Natural Science Foundation of China for groundbreaking work on dermal adipocyte regeneration and wound repair. ๐Ÿ’ก๐Ÿ”ฌ
  • Innovative Contributions: Received support from the Chongqing Natural Science Foundation for advancing research in regenerative medicine. ๐Ÿ’‰๐Ÿ”
  • Recognition for Talent: Honored with the Chongqing Medical Talents: Exceptional Young Talents Project award, highlighting exceptional potential in medical science. ๐Ÿ…๐Ÿ‘ฉโ€๐Ÿ”ฌ
  • National Support: Awarded funding from the National Key Research and Development Program of China for impactful research initiatives. ๐Ÿ‡จ๐Ÿ‡ณ๐Ÿ“Š
  • Academic Funding: Beneficiary of the Fundamental Research Funds for the Central Universities, emphasizing the importance of their research in the academic community. ๐ŸŽ“๐Ÿ“š
Projects๐Ÿ› ๏ธ
  • Dermal Adipocyte Regeneration and Wound Repair: Investigating the mechanisms and potential therapies for skin regeneration and healing. ๐Ÿฉน๐Ÿ”ฌ
  • National Natural Science Foundation Projects: Research focused on enhancing knowledge and treatment approaches in regenerative medicine. ๐Ÿงฌ๐Ÿ’ก
  • Chongqing Natural Science Foundation Initiatives: Developing innovative strategies for improving wound healing and tissue regeneration. ๐ŸŒŸ๐Ÿงช
  • Chongqing Medical Talents: Exceptional Young Talents Project: Promoting advanced research and development in medical science. ๐Ÿ†๐Ÿ‘จโ€๐Ÿ”ฌ
  • National Key Research and Development Program of China: Working on key research projects aimed at solving major scientific and medical challenges. ๐Ÿ‡จ๐Ÿ‡ณ๐Ÿ”
  • Fundamental Research Funds for the Central Universities: Conducting fundamental research in biomedical sciences with a focus on practical applications. ๐ŸŽ“๐Ÿ”Ž
Publications top noted๐Ÿ“œ
  • The mechano-chemical circuit in fibroblasts and dendritic cells drives basal cell proliferation in psoriasis
    Authors: Jiang, J., Shao, X., Liu, W., Chen, J., Lei, M.
    Journal: Cell Reports
    Year: 2024
    Citations: 0
    Link: [Disabled]
  • Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging
    Authors: Zhou, S., Li, Z., Li, X., Chuong, C.-M., Lei, M.
    Journal: Journal of Advanced Research
    Year: 2024
    Citations: 0
    Link: [Disabled]
  • Epidermalโ€“dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures
    Authors: Lei, M., Jiang, J., Wang, M., Yang, L., Chuong, C.-M.
    Journal: npj Regenerative Medicine
    Year: 2023
    Citations: 2
    Link: [Disabled]
  • Mechanical stimuli-induced CCL2 restores adult mouse cells to regenerate hair follicles
    Authors: Wu, W., Zhou, W., Jiang, J., Yang, L., Lei, M.
    Journal: Molecular Therapy Nucleic Acids
    Year: 2023
    Citations: 2
    Link: [Disabled]
  • COX2-ATP Synthase Regulates Spine Follicle Size in Hedgehogs
    Authors: Zhang, M., Wang, M., Jiang, J., Zhou, W., Lei, M.
    Journal: International Journal of Biological Sciences
    Year: 2023
    Citations: 1
    Link: [Disabled]
  • The mechano-chemical circuit drives skin organoid self-organization
    Authors: Lei, M., Harn, H.I.-C., Li, Q., Gu, Z.-Z., Chuong, C.-M.
    Journal: Proceedings of the National Academy of Sciences of the United States of America
    Year: 2023
    Citations: 3
    Link: [Disabled]
  • Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development
    Authors: Wang, M., Zhou, X., Zhou, S., Yang, L., Lei, M.
    Journal: Theranostics
    Year: 2023
    Citations: 4
    Link: [Disabled]
  • Environmental Regulation of Skin Pigmentation and Hair Regeneration
    Authors: Wu, W., Yang, J., Tao, H., Lei, M.
    Journal: Stem Cells and Development
    Year: 2022
    Citations: 5
    Link: [Disabled]