Professor | Pamukkale University Medical Faculty | Turkey
Professor Aylin Köseler is a distinguished academic in the field of biophysics and molecular genetics, currently serving in the Department of Biophysics at Pamukkale University Faculty of Medicine. Her extensive research career spans over two decades, focusing on the molecular mechanisms underlying genetic variability, pharmacogenomics, and disease susceptibility. She has made significant contributions to understanding gene–environment interactions, genetic polymorphisms, and epigenetic regulations associated with cardiovascular diseases, metabolic disorders, and infectious diseases such as COVID-19. Prof. Köseler has led and participated in numerous national and international research projects, including collaborations with prestigious institutions such as Harvard Medical School and the University of California, Los Angeles (UCLA). Her notable involvement in projects like Whole Genome Sequencing of Ancient DNA and Epigenetics in Identical Twins and COVID-19 Patients demonstrates her commitment to interdisciplinary science bridging genetics, biophysics, and clinical medicine. Throughout her academic tenure, she has supervised graduate research and contributed to advancing biomedical science through experimental and computational biophysics approaches. She has authored and co-authored numerous peer-reviewed publications and presented her work at scientific conferences worldwide. Her research outputs have been recognized for their scientific rigor and impact on personalized medicine, population genetics, and evolutionary biology. Beyond academic excellence, Prof. Köseler’s work has substantial societal implications, particularly in improving diagnostic precision, therapeutic efficacy, and public health outcomes. Her dedication to fostering young researchers and promoting collaborative innovation underscores her leadership in the Turkish and international scientific communities. Her ongoing projects continue to explore genetic determinants of complex diseases and epigenetic modulation, contributing valuable insights to the global biomedical research landscape.
Profiles: Google Scholar | Scopus | ORCID | ResearchGate | LinkedIn
Featured Publications
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Sabirli, R., Köseler, A., Goren, T., Turkcuer, I., & Kurt, O. (2021). High GRP78 levels in COVID-19 infection: A case-control study. Life Sciences, 265, 118781. https://doi.org/10.1016/j.lfs.2020.118781 — Cited by: 128
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Palmeira, A., Sousa, E., Köseler, A., Sabirli, R., Gören, T., Türkçüer, İ., Kurt, Ö., et al. (2020). Preliminary virtual screening studies to identify GRP78 inhibitors which may interfere with SARS-CoV-2 infection. Pharmaceuticals, 13(6), 132. https://doi.org/10.3390/ph13060132 — Cited by: 77
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Köseler, A., Sabirli, R., Gören, T., Türkçüer, İ., & Kurt, Ö. (2020). Endoplasmic reticulum stress markers in SARS-CoV-2 infection and pneumonia: Case-control study. In Vivo, 34(3 Suppl), 1645–1650. https://doi.org/10.21873/invivo.11938 — Cited by: 75
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Akca, H., Demiray, A., Yaren, A., Bir, F., Koseler, A., Iwakawa, R., Bagci, G., et al. (2013). Utility of serum DNA and pyrosequencing for the detection of EGFR mutations in non-small cell lung cancer. Cancer Genetics, 206(3), 73–80. https://doi.org/10.1016/j.cancergen.2013.05.012 — Cited by: 58
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Atalay, E. Ö., Koyuncu, H., Turgut, B., Atalay, A., Yildiz, S., Bahadir, A., & Köseler, A. (2005). High incidence of Hb D-Los Angeles [β121 (GH4) Glu→ Gln] in Denizli Province, Aegean region of Turkey. Hemoglobin, 29(4), 307–310. https://doi.org/10.1080/03630260500217438 — Cited by: 50
